Cart summary

You have no items in your shopping cart.

AS1517499

SKU: orb1223648

Description

A novel potent STAT6 inhibitor with IC50 of 21 nM in STAT6-dependent promoter reporter assay; inhibits IL-4-induced Th2 differentiation of mouse spleen T cells with IC50 of 2.3 nM, without influencing Th1 differentiation induced by IL-12; completely inhibits both the antigen-induced up-regulation of RhoA and BSM hyperresponsiveness, significantly inhibits antigen-induced production of IL-13 in mice.

Images & Validation

Key Properties

CAS Number919486-40-1
MW397.8581
Purity>98% (HPLC)
FormulaC20H20ClN5O2
SMILESc1ccc(cc1)CNc2c(cnc(n2)NCCc3ccc(c(c3)Cl)O)C(=O)N
TargetSTAT
SolubilityDMSO: ≥ 35 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AS-1517499 | AS 1517499

Similar Products

  • AS1517499 [orb1302826]

    99.30% (May vary between batches)

    919486-40-1

    397.86

    C20H20ClN5O2

    5 mg, 10 mg, 25 mg, 50 mg, 2 mg, 1 mg, 1 ml x 10 mM (in DMSO), 100 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

AS1517499 (orb1223648)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 90.00
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 350.00
50 mg
$ 540.00
100 mg
$ 660.00