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γ-Asarone

SKU: orb1680812

Description

γ-Asarone is a phenylpropene natural product that demonstrates cytotoxic activity against human melanoma (SK-MEL-2) and lung carcinoma (A549) cell lines in vitro. This compound is utilized in cancer research, particularly in studies investigating apoptosis and cell proliferation mechanisms.

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Key Properties

CAS Number5353-15-1
MW208.25
Purity99.67%
FormulaC12H16O3
SMILESCOc1cc(OC)c(OC)cc1CC=C
TargetOthers

Bioactivity

In Vitro
Even in the Salmonella strains expressing human sulfotransferase (SULT), neither γ-Asarone nor 1'-OH-γ-Asarone showed any mutagenic effect; in contrast, 1'-hydroxymethyleugenol (1'-OH-methyleugenol), used as a positive control, exhibited mutagenicity under these conditions. These results indicate that propenyllic asarones exert genotoxicity through the metabolic formation of side-chain epoxides; whereas for allylic γ-asarone, either its side-chain hydroxylation/sulfonation pathway is not operative, or this pathway does not lead to its mutagenicity .

Storage & Handling

Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Isoasarone, Gamma-Asarone, r-Asarone, soasarone, γ Asarone, γAsarone, γ-Asarone
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Key Properties

No computed properties available.

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γ-Asarone (orb1680812)

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1 mg
$ 100.00
5 mg
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10 mg
$ 220.00
25 mg
$ 410.00
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