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Asperuloside

SKU: orb1222703

Description

Asperuloside has anti-inflammatory activity.

Images & Validation

Key Properties

CAS Number14259-45-1
MW414.36
Purity>98% (HPLC)
FormulaC18H22O11
SMILESC(=O)(C)OCC1=C[C@@H]2OC(=O)C3=CO[C@H]([C@H]1[C@H]23)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO
TargetOthers
SolubilityIn Vitro: DMSO : 100 mg/mL (241.34 mM)

Bioactivity

In Vivo
Animal model: Rats consuming a high fat diet (HFD). Dosage: 3 mg/day. Administration: p.o. , 0.3% in diet, daily, 12 weeks. Result: Reduced body weight, energy intake, adiposity, blood glucose, and plasma insulin.
In Vitro
Western blot analysis. Cell line: U937 cells. Concentration: 0-5 mM. Incubation time: 24 h. Result: Increased the cleaved Caspase-3, Caspase-9, and PARP, and Cyto-c release from mitochondria. Induced expression of GRP78, p-PERK, p-eIF2α, CHOP, p-IRE1, XBP1, ATF6 and cleaved Caspase-12

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Asperuloside (orb1222703)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

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200 mg
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5 mg
$ 100.00
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$ 160.00
25 mg
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50 mg
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100 mg
$ 590.00