ATF1 (C) Antibody, Rabbit Polyclonal

SKU: orb66962

Description

Rabbit polyclonal to ATF1.ATF1 is an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma (provided by RefSeq and Uniprot)

Images & Validation

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Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human ATF1
Molecular Weight	29
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-ATF1 antibody,anti-Cyclic AMPdependent transcription factor ATF1 antibody,anti-cAMPdependent transcription factor ATF1 antibody,anti-Activating transcription factor 1 antibody,anti-Protein TREB36 antibody

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Western blot analysis of total cell extracts from human Hela using ATF1 antibody

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UniProt

P18846

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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