Atiprimod (free base)

SKU: orb1738304

Description

Atiprimod is an orally active azaspirane that inhibits STAT3 phosphorylation, disrupting IL-6 and VEGF signaling. This action downregulates anti-apoptotic proteins like Bcl-2, leading to cell cycle arrest and apoptosis in various cancer models, as demonstrated in both in vitro and in vivo studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

−

Key Properties

−

CAS Number	123018-47-3
MW	336.6
Formula	C₂₂H₄₄N₂
SMILES	C(CCN(CC)CC)N1CC2(CCC(CCC)(CCC)CC2)CC1
Target	PERK,Others,JAK,ATG,ROS,STAT,p62,PARP,Bcl-2 Family,NF-κB,Apoptosis,Caspase,Autophagy

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Compound Identifiers

PubChem CID

129869 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols