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Avadomide HCl

SKU: orb1701147

Description

Avadomide (CC-122) is a cereblon-binding immunomodulatory agent that degrades Ikaros and Aiolos, exhibiting direct antitumor and immunostimulatory effects. Its activity against diffuse large B-cell lymphoma (DLBCL) has been demonstrated in both in vitro and in vivo models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number1398053-45-6
MW322.75
FormulaC14H15ClN4O3
SMILESCl.O=C1NC(=O)C(N2C(=O)C3=C(N=C2C)C=CC=C3N)CC1
TargetMolecular Glues,Others,E1/E2/E3 Enzyme,NF-κB,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Avadomide HCl (orb1701147)

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