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Avitinib maleate

SKU: orb1303846

Description

Avitinib maleate

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1557268-88-8
MW603.61
Purity99.77%
FormulaC30H30FN7O6
SMILESOC(=O)\C=C/C(O)=O.CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c3cc[nH]c3n2)cc1F
TargetApoptosis,BTK,EGFR
SolubilityDMSO:300 mg/mL (497.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.28 mM)

Bioactivity

Target IC50
EGFR L858R/T790M:0.18 nM|EGFR:7.68 nM|EGFR (WT):7.68 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AC0010, AC-0010, AC 0010, Abivertinib, Avitinib, Avitinib Maleate, Avitinib maleate, Epidermal growth factor receptor, EGFR, ErbB-1, HER1, Inhibitor, inhibit

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Key Properties

No computed properties available.

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Avitinib maleate (orb1303846)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 160.00
25 mg
$ 260.00
50 mg
$ 420.00
100 mg
$ 640.00
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