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AZ-GHS-38

SKU: orb3174700

Description

AZ-GHS-38 (compound 38) is an orally active inverse agonist of the growth hormone secretagogue receptor (GHS-R1a) that can cross the blood-brain barrier, with an IC50 of 6.7 nM. It has been shown to acutely reduce food intake in wild-type mice and may be used for anti-obesity research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1143021-16-2
MW578.1
FormulaC25H28ClN5O5S2
SMILESO=C(NC(=O)C1=CC(=CC=C1Cl)N2CCOCC2)NC3=NC=4C=CC(=CC4S3)S(=O)(=O)C5CCN(C)CC5
TargetGHSR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information