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AZ13581837

SKU: orb3211008

Description

AZ13581837 is an orally active GPR120 agonist with an EC50 of 5.2 nM for human receptors and 4.3 nM for mouse receptors. It mediates signaling through Gαq, Gαs, and β-arrestin pathways, inhibiting cAMP production, promoting GLP-1 secretion, lowering blood glucose levels, and enhancing insulin secretion. AZ13581837 can be used in research related to type 2 diabetes.

Images & Validation

Key Properties

CAS Number2896777-27-6
MW362.40
FormulaC20H14N2O3S
SMILESO=S1(=O)C=2C=CC=CC2CN1C=3C=C(C#C)C=C(OC=4C=NC=CC4)C3
TargetGPCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information