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AZD8421

SKU: orb2695185

Description

AZD8421 is a potent, selective CDK2 inhibitor (IC50 = 9 nM) that suppresses Rb phosphorylation and cell proliferation. It demonstrates significant antitumor activity in breast and ovarian cancer models, both alone and combined with CDK4/6 inhibitors, supporting its use in oncology research.

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Key Properties

CAS Number3047321-53-6
MW440.56
FormulaC18H32N8O3S
SMILESN(C1=C2C(N(CC)C=N2)=NC(N[C@H]([C@@H](C)O)CC)=N1)[C@@H]3CN(S(NCC)(=O)=O)CC3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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AZD8421 (orb2695185)

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