Bacopasaponin C

SKU: orb1297448

Description

Bacopasaponin C is a natural triterpenoid saponin with demonstrated antioxidant and anti-leishmanial properties. It is a research tool for studying oxidative stress and parasitic infections, with applications in both in vitro assays and in vivo experimental models for infectious disease research.

Research Area

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	178064-13-6
MW	899.07
Purity	99.17% (May vary between batches)
Formula	C₄₆H₇₄O₁₇
SMILES	[H][C@@]1(O[C@@H]2[C@@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)CO[C@@]2([H])O[C@H]2CC[C@@]3(C)[C@@]([H])(CC[C@]4(C)[C@]3([H])CC[C@]3([H])[C@]5([H])[C@]6(C[C@@]43CO6)OC[C@@H](C=C(C)C)[C@]5(C)O)C2(C)C)O[C@@H](CO)[C@H](O)[C@H]1O
Target	P-gp,GABA Receptor,Parasite,Anti-infection,NMDAR
Solubility	DMSO:60 mg/mL (66.74 mM)

Bioactivity

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In Vitro

Chemical characterization studies revealed the major active constituents of the herb as the triterpenoid saponins, bacosides. Bacoside A, the vital neuroprotective constituent, is composed of four constituents viz., bacoside A3, bacopaside II, jujubogenin isomer of Bacopasaponin C (bacopaside X) and Bacopasaponin C. B. monnieri extracts as well as bacosides successfully establish a healthy antioxidant environment in various tissues especially in liver and brain. Free radical scavenging, suppression of lipid peroxidation and activation of antioxidant enzymes by bacosides help to attain a physiological state of minimized oxidative stress. The molecular basis of neuroprotective activity of bacosides is attributed to the regulation of mRNA translation and surface expression of neuroreceptors such as AMPAR, NMDAR and GABAR in the various parts of the brain. Bioavailability as well as binding of neuroprotective agents (such as bacosides) to these receptors is controlled by the Blood Brain Barrier (BBB). However, nano conversion of these drug candidates easily resolves the BBB restriction and carries a promising role in future therapies

Storage & Handling

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Storage	keep away from direct sunlight,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Bacopasaponin C, Antifection, Anti-infection, Antiinfection, Parasite, NMDAR, NMDA receptor, inhibit, Inhibitor, GABA, GABA Receptor, GABAReceptor

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Compound Identifiers

PubChem CID

21599443 ↗

Key Properties

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No computed properties available.

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Bacopasaponin C (orb1297448)

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Purity:	>98% (HPLC)
CAS Number:	178064-13-6
MW:	899.08
Formula:	C₄₆H₇₄O₁₇

Bacopasaponin C

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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