Bat coronavirus BANAL20-236 Spike Trimer Protein (R677A, K978P, V979P), His Tag (MALS verified)

SKU: orb3158197

Description

The spike protein of bat coronavirus BANAL-20-236, a SARS-CoV-2–related sarbecovirus identified in Laos, mediates viral entry by promoting receptor attachment and membrane fusion. BANAL-20-236 shares high genomic similarity with SARS-CoV-2 and contains spike features relevant to cross-species transmission. Specific substitutions, such as P804L in the S2 subunit, have been linked to adaptation to a broad range of Rhinolophus bat ACE2 receptors, making it important for studies on coronavirus evolution and zoonotic spillover risk.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.3 kDa. The protein migrates as >130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

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Expression System	HEK293
Target	Spike protein
Tag	C-10×His
Molecular Weight	137.3 kDa
Expression Region	Ser 14 - Pro 1205
Purity	90%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	0.1 M Sodium citrate, pH 5.5
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Spike protein

RefSeq:K978, V979, UAY13253.1, R677

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	K978, V979, UAY13253.1, R677

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