Bat coronavirus RS4081 Spike Trimer Protein (R653A, K954P, V955P), His Tag (MALS verified)

SKU: orb3158200

Description

The spike protein of bat coronavirus RS4081, a sarbecovirus related to SARS-CoV, mediates viral entry by facilitating attachment and membrane fusion. RS4081’s spike can support ACE2-independent, trypsin-dependent cell entry, highlighting alternative pathways for host infection and its potential relevance to zoonotic spillover and cross-species transmission studies.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 134.9 kDa. The protein migrates as 150-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	Spike protein
Tag	C-10×His
Molecular Weight	134.9 kDa
Expression Region	Gln 16 - Pro 1181
Purity	90%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	0.1 M Sodium citrate, pH 5.5
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Spike protein

RefSeq:V955, K954, ATO98120.1, R653

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	V955, K954, ATO98120.1, R653

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