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BChE-IN-20

SKU: orb1941854

Description

BChE-IN-20 (compound 7c) is a potent and selective inhibitor of BChE, with IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 μM. BChE-IN-20 serves as a promising template for the design and development of pharmaceutical BChE-selective ligands, including inhibitors and fluorogenic probes.

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Key Properties

CAS Number1428439-79-5
MW465.63
FormulaC27H39N5O2
SMILESO=C(OC)C1=CN(CCC=2N=C(N=C(NCCCN(CC)CC)C2C1)C=3C=CC=CC3)C(C)C
TargetCholinesterase (ChE),Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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BChE-IN-20 (orb1941854)

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