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BDM71230

SKU: orb3210596

Description

BDM71230 is an orally active inducer of the Insulin-Degrading Enzyme (IDE), with an EC50 of 1.9 μM for human IDE. This compound binds to the IDE dimer interface, enhancing IDE's catalytic activity through spatial interaction. BDM71230 boosts the hydrolysis of insulin by IDE while slightly diminishing insulin's hypoglycemic effect. It serves as a pharmacological tool for investigating IDE functions, particularly in studies related to glucose intolerance.

Images & Validation

Key Properties

TargetIGF-1R

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information