Beclomethasone 17-propionate

SKU: orb1992940

Description

Beclomethasone 17-propionate is a glucocorticoid that is the active metabolite of Beclomethasone dipropionate (BDP). As a glucocorticoid receptor (GR) agonist, 17-BMP has a 13-fold higher affinity than BDP and inhibits the production of pro-inflammatory cytokines, such as CXCL8, TNF-α, and IL-6, thus exerting an anti-inflammatory effect, and it is mainly used in the treatment of asthma and allergic rhinitis.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	5534-18-9
MW	464.98
Purity	98.06%
Formula	C₂₅H₃₃ClO₆
SMILES	O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Target	Glucocorticoid Receptor,Drug Metabolite

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Glucocorticoid Receptor,Drug Metabolite

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