Benorilate

Benorylate (Benoral) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis.(In Vitro):Benorylate (Salipran) is an esterified aspirin preparation whose antirheumatic properties are reported to be as good as those of aspirin.Benorylate (Salipran) causes a large decrease in the liver’s conversion rate of lactate into glucose, an important component of glucose homeostasis. Benorylate (Salipran) also impairs the urea synthesis rate from ammonia, another important function of the liver.(In Vivo):Benorylate (Salipran) is probably absorbed as the intact molecule which accounts for its good gastric tolerance.Benorylate (Salipran) could inhibit PG synthesis in laboratory animals and in human tissue.