Berbamine dihydrochloride

SKU: orb1304843

Description

Berbamine dihydrochloride is a natural bisbenzylisoquinoline alkaloid isolated from Berberis amurensis, demonstrating antitumor properties. It is utilized in cancer research, with studies reporting its ability to induce autophagy and apoptosis in various cancer cell lines in vitro and inhibit tumor growth in vivo.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	6078-17-7
MW	681.65
Purity	99.99%
Formula	C₃₇H₄₂Cl₂N₂O₆
SMILES	COC1=C2C3=C(CCN([C@]3([H])CC4=CC=C(O)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CCN6C)OC)C=C5)=C4)C)C=C1OC.Cl.Cl
Target	Autophagy,Bcr-Abl,NF-κB,Apoptosis
Solubility	DMSO:135 mg/mL (198.05 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.87 mM)

Storage & Handling

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Storage	keep away from direct sunlight,store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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NF-κB, NFkB, NF-kB, NFκB, Abl, BcrAbl, Apoptosis, Autophagy, dihydrochloride, Berbamine, Berbamine 2HCl

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Compound Identifiers

PubChem CID

16217067 ↗

Key Properties

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No computed properties available.

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