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Berotralstat

SKU: orb1694247

Description

Berotralstat (BCX7353) is a potent and selective oral plasma kallikrein inhibitor used in hereditary angioedema (HAE) research. It blocks bradykinin release, mitigating swelling and pain, and has demonstrated efficacy in both in vitro enzymatic assays and in vivo preclinical models of HAE.

Research Area

Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1809010-50-1
MW562.56
FormulaC30H26F4N6O
SMILESNCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)[C@H](NCC1CC1)c1cccc(c1)C#N)C(F)(F)F
TargetOthers,Serine Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information