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(+)-Bicuculline methiodide

SKU: orb1704660

Description

(+)-Bicuculline methiodide is a blood-brain barrier permeable GABAA receptor antagonist used to induce and study seizure activity in models of epilepsy. Its application extends to neuropharmacological research, where it is employed in both in vitro electrophysiology and in vivo studies investigating neurological disorders and septic pathophysiology.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number40709-69-1
MW509.29
Purity99.24% (May vary between batches)
FormulaC21H20INO6
SMILESC[N+]1(C)[C@]([C@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[I-]
TargetGABA Receptor
SolubilityDMSO:<25.46 mg/mL;H2O:<10.19 mg/ml

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Bicuculline methiodide, ()Bicuculline methiodide, ( ) Bicuculline methiodide, d-Bicuculline methiodide, N-Methylbicuculline iodide, GABAReceptor, GABA Receptor, GABAA
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 70.00
DispatchUsually dispatched within 5-10 working days
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