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Bimekizumab Antibody

SKU: orb1980645

Description

Bimekizumab is a humanized monoclonal antibody that simultaneously neutralizes IL-17A and IL-17F. It is a valuable research tool for studying psoriatic and arthritic disease mechanisms, supporting both in vitro assays of cytokine blockade and in vivo models of inflammation and bone biology.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1418205-77-2
MW147.24 kDa
Purity100.00%
TargetIL Receptor,Interleukin

Bioactivity

In Vitro
Methods: Bimekizumab (10 μg/mL, 1 hour) was used to treat human periosteum-derived cells (hPDCs), and the expression of osteogenesis-related genes was analyzed by real-time quantitative PCR. Results: Bimekizumab effectively suppressed the expression of osteogenic genes through dual neutralization of IL-17A and IL-17F.

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

THPTA

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Bimekizumab Antibody (orb1980645)

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Available Sizes

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1 mg
$ 420.00
5 mg
$ 830.00
10 mg
$ 1,270.00
DispatchUsually dispatched within 5-10 working days
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