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Biotin-PEG4-N3

SKU: orb1220156

Description

Biotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Key Properties

CAS Number875770-34-6
MW444.55
Purity>98% (HPLC)
FormulaC??H??N?O?S
SMILESO=C(NCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
TargetPROTAC
SolubilityIn Vitro: DMSO : 100 mg/mL (224.95 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Biotin-PEG4-N3 (orb1220156)

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