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BPR3P0128

SKU: orb2566778

Description

BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1345406-09-8
MW436.30
FormulaC22H18BrN3O2
SMILESCC1=C(C2=NC3=C(C(C(O)=O)=C2)C=C(Br)C=C3)C=NN1C4=C(C)C=CC(C)=C4
TargetSARS-CoV

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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BPR3P0128 (orb2566778)

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