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Brevianamide F

SKU: orb1304423

Description

Brevianamide F, a natural 2,5-diketopiperazine also known as cyclo(L-Pro-L-Trp), is a research chemical noted for its inhibitory activity against the breast cancer resistance protein (BCRP). It is utilized in vitro to study multidrug resistance mechanisms and probe BCRP function in oncology research.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number38136-70-8
MW283.33
Purity98.82% (May vary between batches)
FormulaC16H17N3O2
SMILESO=C1N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N2CCC[C@@H]12
TargetPI3K,BCRP,Antibacterial
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.06 mM);DMSO:50 mg/mL (176.47 mM)

Bioactivity

Target IC50
PI3Kα:4.8 μM (IC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

breast cancer resistance protein, Brevianamide F, Cyclo(L-Pro-L-Trp), cyclo-(L-Trp-L-Pro), Cyclo-L-tryptophyl-L-proline, antibacterial, Bacterial, inhibit, mycotoxin, Inhibitor, PI3Kα, PI3K, Phosphoinositide 3-kinase

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  • Brevianamide F [orb1225147]

    >98% (HPLC)

    38136-70-8

    283.3251

    C16H17N3O2

    1 g, 500 mg, 200 mg, 5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 2 mg
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Key Properties

No computed properties available.

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Protocol Information

Brevianamide F (orb1304423)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 110.00
10 mg
$ 130.00
25 mg
$ 210.00
50 mg
$ 300.00
100 mg
$ 460.00
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