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Butibufen

SKU: orb1700939

Description

Butibufen (FF-106) is an orally bioavailable, non-steroidal anti-inflammatory agent that acts as a cyclooxygenase inhibitor with analgesic and antipyretic properties. It has been utilized in research models of rheumatic disease and has demonstrated inhibitory effects on urea synthesis in experimental studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number55837-18-8
MW220.31
Purity98.91%
FormulaC14H20O2
SMILESO=C(O)C(C1=CC=C(C=C1)CC(C)C)CC
TargetOthers,Lipoxygenase,Urea Transporter

Bioactivity

In Vivo
In Sprague-Dawley rats, Butibufen (50 and 250 mg/kg; oral gavage) reduces acid phosphatase activity but does not affect the stability of lysosomal membranes.
In Vitro
In hepatocytes from Sprague-Dawley male rats, Butibufen (0.1 μM-0.1 M; 60 min) exhibited no cell viability effects at a dose of 200 μM, but dose- and time-dependently affected cell viability at higher concentrations.

Storage & Handling

StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Butibufen, LOX, FF106, FF-106, FF 105, FF 106
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

Butibufen (orb1700939)

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Available Sizes

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1 mg
$ 80.00
5 mg
$ 120.00
10 mg
$ 150.00
25 mg
$ 220.00
50 mg
$ 310.00
100 mg
$ 440.00
500 mg
$ 990.00
DispatchUsually dispatched within 6-8 weeks
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