Butoconazole nitrate

SKU: orb1224351

Description

Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.(In Vitro):Imidazoles generally inhibit the conversion of lanosterol to ergosterol, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell.

Images & Validation

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Key Properties

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CAS Number	64872-77-1
MW	474.79
Purity	>98% (HPLC)
Formula	C₁₉H₁₈Cl₃N₃O₃S
SMILES	ClC1=C(SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O
Target	Estrogen Receptor/ERR
Solubility	DMSO: 95 mg/mL (200.08 mM)

Bioactivity

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In Vitro	Imidazoles generally inhibit the conversion of lanosterol to ergosterol, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell. Read more...

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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(±)-Butoconazole | RS-35887

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Gene Symbol

Estrogen Receptor/ERR

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