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C14-Tri-LAN-Gly

SKU: orb3175155

Description

C14-Tri-LAN-Gly is a highly selective and efficient NOD1 agonist. It activates NOD1 and inhibits the expression of cleaved-caspase3 while upregulating A20 expression. By preventing hepatocyte apoptosis (Apoptosis), C14-Tri-LAN-Gly protects mice from lethal hepatitis. Additionally, it inhibits osteoblast formation and promotes osteoclast generation.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1863978-69-1
MW675.84
FormulaC30H53N5O10S
SMILES[C@H](NC(CC[C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)C)=O)C(O)=O)=O)(C(NCC(O)=O)=O)CSC[C@@H](C(O)=O)N
TargetApoptosis,Caspase,NOD-like Receptor (NLR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information