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C188

SKU: orb1700931

Description

C188 is a cell-permeable, small-molecule STAT3 inhibitor that selectively blocks IL-6-induced STAT3 phosphorylation and nuclear translocation by targeting its SH2 domain. It is a valuable research tool for studying STAT3-dependent signaling in cancer and inflammation, with demonstrated utility in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number823828-18-8
MW433.45
FormulaC19H15NO7S2
SMILESOC(=O)CSc1cc(NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2c1O
TargetOthers,Apoptosis,STAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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C188 (orb1700931)

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