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(-)-Carvone

SKU: orb1940115

Description

(-)-Carvone is a natural product which probably has antioxidant and anti-inflammatory capabilities.

Images & Validation

Key Properties

CAS Number6485-40-1
MW150.221
Purity>98% (HPLC)
FormulaC10H14O
SMILESCC(=C)[C@@H]1CC=C(C)C(=O)C1
SolubilityIn Vitro: DMSO : 100 mg/mL (665.69 mM)

Bioactivity

In Vivo
(-)-Carvone (5% in absolute ethanol v/v, 20 μL; application to the thoraces ventral surfaces) inhibits AChE such as horse serum cholinesterase, house fly head cholinesterases, and head and thorax cholinesterases from the Madagascar roach in vitro. (-)-Carvone (0.05%-0.1% w/v; p.o. ; 7 d) inhibits E. insulana larvae growth, decreases weight of larvae. Animal model: Female roaches (Gromphadorhina portentosa) (6.4 g-6.8 g). Dosage: 5% in absolute ethanol v/v, 20 μL. Administration: Application to the ventral surfaces of their thoraces; decapitated and crude at various time intervals (0, 2, 4, 5, 20, 24, and 26 hr). Result: Inhibited the activity of AChE in the extracts of both the head and thorax.
In Vitro
(-)-Carvone (3.04 mM; 30 min) inactivates eel AChE with Ki value of 2.19 mM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information