CASP3 Activator 1541

SKU: orb1298743

Description

CASP3 Activator 1541 is a small molecule that activates pro-caspase-3, initiating the caspase cascade and leading to apoptotic cell death. It is a valuable research tool for studying apoptosis mechanisms in both cellular (in vitro) and animal (in vivo) models of cancer and neurodegenerative diseases.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	1100353-03-4
MW	411.41
Purity	99.98%
Formula	C₂₄H₁₇N₃O₄
SMILES	COc1cccc2cc(C(=O)Nc3cccc(c3)-c3cn4ccccc4n3)c(=O)oc12
Target	Caspase
Solubility	H2O:Insoluble;DMSO:4.12 mg/mL (10.01 mM)

Bioactivity

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Target IC50	Procaspase-3:2.4 ± 0.2 μM (EC50)\|Procaspase-6:2.8 ± 0.3 μM (EC50)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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CASP3 Activator 1541, CASP-3 Activator 1541, caspase-3

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Compound Identifiers

PubChem CID

43816622 ↗

Key Properties

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No computed properties available.

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