Cart summary

You have no items in your shopping cart.

CB-1158-analog

SKU: orb1738552

Description

CB-1158-analog (INCB01158-analog) is a potent, orally bioavailable arginase inhibitor. It blocks myeloid-derived suppressor cell (MDSC) activity, enhancing anti-tumor immunity by increasing tumor-infiltrating CD8+ T and NK cells in vivo. This mechanism supports its research in cancer immunotherapy, including combinations with checkpoint inhibitors and chemotherapy in various cancer models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1345810-21-0
MW417.14
FormulaC18H27BCl2N2O4
SMILESC(CCCCB(O)O)(C(O)=O)(N)C1CCN(CC2=C(Cl)C=C(Cl)C=C2)CC1
TargetArginase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

CB-1158-analog (orb1738552)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%