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CCL-34

SKU: orb3136019

Description

CCL-34 is an activator of Toll-like receptor 4 (TLR4). It significantly induces the expression of CD83 on dendritic cells (DC) and the production of IL-12p70 in a dose-dependent manner, thereby promoting DC maturation. CCL-34 enhances the allostimulatory activity of DC on the proliferation of naive CD4+CD45+RA+ T cells and their secretion of IFN-γ. Furthermore, CCL-34 can enhance antigen presentation capability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 is applicable for research in immune stimulation.

Images & Validation

Key Properties

CAS Number943316-60-7
MW602.84
FormulaC32H62N2O8
SMILESO(C[C@@H](C(NCCCCCCCCCCC)=O)NC(CCCCCCCCCCC)=O)[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
TargetTLR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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CCL-34 (orb3136019)

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