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CD2 Antibody

SKU: orb1824669

Description

CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

Images & Validation

Tested ApplicationsIHC-P
Dilution RangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
ReactivityHuman
Application Notes
Optimal dilution of the CD2 antibody should be determined by the researcher.

Key Properties

Antibody TypePrimary Antibody
HostRabbit
ClonalityRecombinant
IsotypeRabbit IgG, kappa
Clone No.LFA2/8681R
ImmunogenA recombinant fragment corresponding to the N-terminal of human CD2 protein was used as the immunogen for the CD2 antibody.
PurificationProtein A/G affinity
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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CD2 Antibody

IHC staining of FFPE human spleen tissue with CD2 antibody (clone LFA2/8681R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

CD2 Antibody

SDS-PAGE analysis of purified, BSA-free CD2 antibody (clone LFA2/8681R) as confirmation of integrity and purity.

UniProt Details

No UniProt data available

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Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol

CD2 Antibody (orb1824669)

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20 μg
$ 370.00
100 μg
$ 750.00
DispatchUsually dispatched within 5-10 working days
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