CDC37 Antibody (Biotin)

SKU: orb151598

Description

Rabbit polyclonal to CDC37 (Biotin). Hsp90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies.

Research Area

Cancer Biology, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Images & Validation

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Item 1 of 3

Tested Applications	ICC, IF, IHC
Dilution Range	WB (1:2000), ICC/IF (1:200)
Reactivity	Human
Application Notes	A 1:2000 dilution was sufficient for detection of cdc37 in 20 µg of HeLa cell lysate by ECL immunoblot analysis.

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	Native human Cdc37, full length
Target	CDC37
Molecular Weight	44.5kDa
Purification	Protein A Purified
Conjugation	Biotin

Storage & Handling

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Storage	Conjugated antibodies should be stored according to the product label
Buffer/Preservatives	136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate.
Concentration	1.68 mg/ml
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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CDC37, Hsp90 co-chaperone Cdc37, Cell division control protein 37, Hsp90 chaperone protein kinase-targeting subunit, CDC37_HUMAN, CDC37A, p50, p50Cdc37, S. cerevisiae hypothetical protein CDC37

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Quick Database Links

Gene Symbol

CDC37

UniProt

Q16543

NCBI Gene ID

11140

RefSeq (Protein):NP_008996.1

UniProt Details

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No UniProt data available

NCBI Gene Details

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No NCBI Gene data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_008996.1

Protocol Information

IHC

Immunohistochemistry

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Immunofluorescence

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ICC

Immunocytochemistry

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100 μg

$ 560.00

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Usually dispatched within 2-3 weeks

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Applications:	ELISA
Reactivity:	Human
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Biotin

Applications:	IF, IHC-Fr, IHC-P, WB
Predicted Reactivity:	Bovine, Canine, Porcine, Rat
Reactivity:	Human, Mouse
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Biotin

Applications:	ICC, IF, IHC-Fr, IHC-P
Predicted Reactivity:	Bovine, Canine, Equine, Gallus, Human, Mouse, Rabbit, Rat, Sheep
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Biotin

CDC37 Antibody (Biotin)

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

Alternative Names

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