CDH1 (C2) Antibody, Rabbit Polyclonal

SKU: orb66765

Description

Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:500-1:1000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human CDH1
Molecular Weight	97
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-CDH1 antibody,anti-Cadherin1 antibody,anti-CAM 120 antibody,anti-80 antibody,anti-Epithelial cadherin antibody,anti-Ecadherin antibody,anti-Uvomorulin antibody,anti-CD324 antibody,anti-CDHE antibody,anti-UVO antibody

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Western blot analysis of total cell extracts from human MCF7(Lane1) and human Hela(Lane2) using CDH1 antibody

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UniProt

P12830

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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WB (1)

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Human (1)

Rui Huang 1, Miao Gao 2 Circ_0070987 Promotes Pyroptosis of Ovarian Granulosa Cells in Polycystic Ovarian Syndrome Through the miR-139-5/CDH1 Axis Reprod Sci ., (2025)

PubMed: 40911155

Applications

Reactivity

Human