Cart summary

You have no items in your shopping cart.

Cephalandole B

SKU: orb1737435

Description

Cephalandole B is a cyanobacterial indole alkaloid that demonstrates dose-dependent inhibition of IL-17A gene expression and reporter activity in Jurkat T-cells. This makes it a useful research tool for studying Th17 cell biology and IL-17-mediated pathways in autoimmune and inflammatory disease models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number915315-44-5
MW294.3
Purity98.98%
FormulaC17H14N2O3
SMILESC(NC1=C(C(OC)=O)C=CC=C1)(=O)C=2C=3C(NC2)=CC=CC3
TargetIL Receptor

Bioactivity

In Vitro
Two indole alkaloids, including one new indigodole D and cephalandole B, were isolated from Qing Dai. Cephalandole B did not inhibit the IL-17A protein secretion. Nevertheless, both isolates notably inhibited IL-17A gene expression, especially cephalandole B, in a dose-dependent manner in Jukat cells with IL-17A luciferase reporter.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

IL Receptor, IL-17A, ILReceptor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Cephalandole B (orb1737435)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 240.00
5 mg
$ 530.00
10 mg
$ 760.00
25 mg
$ 1,130.00
50 mg
$ 1,520.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry