CGS 21680 Hydrochloride

SKU: orb1300765

Description

CGS 21680 HCl is a potent and highly selective adenosine A2A receptor agonist (IC50=22 nM), exhibiting 140-fold selectivity for A2A over A1 receptors. It is widely used in vitro and in vivo to study adenosine signaling, neuroprotection, inflammation, and cardiovascular models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	124431-80-7
MW	535.98
Purity	99.53%
Formula	C₂₃H₂₉N₇O₆·HCl
SMILES	Cl.CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(NCCc3ccc(CCC(O)=O)cc3)nc12
Target	Adenosine Receptor
Solubility	DMSO:53.6 mg/mL (100 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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Inhibitor, inhibit, CGS 21680, CGS 21680 HCl, CGS 21680 Hydrochloride, CGS21680, CGS-21680, CGS21680 Hydrochloride, CGS-21680 Hydrochloride, A2, Adenosine Receptor, AdenosineReceptor, P1 receptor

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Gene Symbol

Adenosine Receptor

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