Cart summary

You have no items in your shopping cart.

Chebulagic acid

SKU: orb1296151

Description

Chebulagic acid is a natural compound derived from Terminalia chebula Retz. that acts as a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes. It is utilized in biochemical research to study inflammation pathways and has shown activity in both in vitro assays and in vivo models of inflammation.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number23094-71-5
MW954.66
Purity97.82%
FormulaC41H30O27
SMILESO[C@H]1[C@H]2[C@H](CC(O)=O)C(=O)O[C@@H]3[C@H]4COC(=O)c5cc(O)c(O)c(O)c5-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]3[C@@H](OC(=O)c3cc(O)c(O)c(OC1=O)c23)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)O4
TargetSARS-CoV,Influenza Virus,Lipoxygenase,COX
Solubility10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.05 mM);DMSO:150 mg/mL (157.12 mM)

Bioactivity

In Vitro
Chebulagic acid can enhance autophagy and exerts anti-inflammatory and anti-infective effects [1,2]. Chebulagic acid also shows a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Chebulagic acid inhibits the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner .

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Chebulagic acid, COX, Cyclooxygenase, InfluenzaVirus, Influenza Virus, Lipoxygenase, inhibit, LOX, Inhibitor, SARS coronavirus, SARS-CoV, SARSCoV

Similar Products

  • Chebulagic acid (Standard) [orb3139946]

    23094-71-5

    954.66

    C41H30O27

    10 mg
  • Chebulagic acid [orb1219423]

    >98% (HPLC)

    23094-71-5

    954.7

    C41H27O27

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Chebulagic acid (orb1296151)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 210.00
10 mg
$ 290.00
1 ml x 10 mM (in DMSO)
$ 310.00
25 mg
$ 460.00
50 mg
$ 670.00
100 mg
$ 930.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry