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Cimetidine

SKU: orb1310283

Description

Cimetidine is a histamine H2 receptor antagonist that competitively inhibits histamine binding, leading to suppressed gastric acid, pepsin, and gastrin secretion. It is widely used in research involving gastrointestinal physiology, ulcer models, and receptor studies in both in vitro and in vivo experimental settings.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number51481-61-9
MW252.34
Purity99.82% (May vary between batches)
FormulaC10H16N6S
SMILESCN\C(NCCSCC1=C(C)NC=N1)=N/C#N
TargetHistamine Receptor,Antibacterial
SolubilityH2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:3 mg/mL (11.89 mM);DMSO:245 mg/mL (970.91 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (9.91 mM)

Bioactivity

Target IC50
Histamine receptor:0.6 μM (Ki)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SKF 92334, SKF92334, SKF-92334, inverse, Inhibitor, inhibit, HistamineReceptor, Histamine Receptor, H2 receptor, Cimetidine, anti-cancer, anti-inflammatory

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Key Properties

No computed properties available.

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Cimetidine (orb1310283)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 90.00
1 g
$ 100.00
DispatchUsually dispatched within 3-5 working days
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