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Clofibrate

SKU: orb1309070

Description

Clofibrate is a synthetic aryloxyisobutyrate derivative that acts as a lipid-lowering agent. It is used in biochemical research to study peroxisome proliferator-activated receptor (PPAR) alpha agonism and lipid metabolism in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number637-07-0
MW242.70
Purity99.87% (May vary between batches)
FormulaC12H15ClO3
SMILESCCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1
TargetPPAR
SolubilityDMSO:50 mg/mL (206.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.24 mM)

Bioactivity

Target IC50
PPARα (human):55 μM(ec50)|PPARγ (human):500 μM (ec50)|PPARα (murine):50 μM (ec50)|PPARγ (murine):500 μM (ec50)

Storage & Handling

StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Clofibrate, Clofibrato, Clofibratum, Ethyl clofibrate, PPARα, PPAR

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Key Properties

No computed properties available.

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Clofibrate (orb1309070)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

200 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
500 mg
$ 90.00
1 g
$ 100.00
5 g
$ 120.00
DispatchUsually dispatched within 3-5 working days
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