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Clozapine N-oxide dihydrochloride

SKU: orb1745121

Description

Clozapine N-oxide dihydrochloride is a blood-brain barrier permeable agonist for the chemogenetic DREADD receptors hM3Dq and hM4Di. It is a key research tool for targeted neuronal manipulation in studies of neural circuits, behavior, and diseases, applicable in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2250025-93-3
MW415.74
Purity99.35% (May vary between batches)
FormulaC18H21Cl3N4O
SMILESC[N+]1(CCN(C2=NC3=CC(Cl)=CC=C3NC4=C2C=CC=C4)CC1)[O-].Cl.Cl
TargetDopamine Receptor,AChR,Drug Metabolite,Cholinesterase (ChE)
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (24.05 mM);H2O:50 mg/mL (120.27 mM);DMSO:200 mg/mL (481.07 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AChE, Clozapine N-oxide, Clozapine N-oxide Dihydrochloride
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 120.00
25 mg
$ 170.00
50 mg
$ 230.00
100 mg
$ 320.00
DispatchUsually dispatched within 5-10 working days
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