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COB-187

SKU: orb2646381

Description

COB-187 is an effective, ATP-competitive, selective inhibitor of GSK-3β. It inhibits GSK-3 through a reversible, cysteine (Cys)-199 dependent mechanism. Additionally, COB-187 suppresses the production of cytokines induced by LPS and the production of CXCL10 triggered by the SARS-CoV-2 spike protein.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1862177-86-3
MW302.41
FormulaC15H14N2OS2
SMILESS=C1SCC(O)(C=2C=CC=CC2)N1CC=3C=CN=CC3
TargetGSK-3

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

COB-187 (orb2646381)

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