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COX-2/15-LOX-IN-1

SKU: orb1687044

Description

COX-2/15-LOX-IN-1 (Compound 14) is a dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 0.075 µM) and 15-lipoxygenase (15-LOX; IC50 = 2.98 µM), with significant selectivity over COX-1. This small molecule exhibits anti-inflammatory activity and is a useful research tool for studying eicosanoid pathways in both cellular and animal models of inflammation.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number2413565-15-6
MW467.63
FormulaC21H21N7S3
SMILESS(C)C=1N(C=2C(N1)=CC=CC2)C=3N=C(NCC(=NNC(NC4=CC=CC=C4)=S)C)SC3
TargetOthers,COX,Lipoxygenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

COX-2/15-LOX-IN-1 (orb1687044)

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