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Curcumin

SKU: orb1308370

Description

Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, anti-inflammatory and antioxidant.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology

Customer Validated Data

The data below is submitted by researchers worldwide. We provide this transparency to help you decide if this antibody works for your specific application or species, even if we haven't tested it ourselves.
Success by Application
Reactivity Distribution

Latest Experiments

5 Results
Dilution
Sample
Summary
Enzymatic glycosylation assay
Chemical
-
Curcuma longa L. (turmeric)
For sample preparation, curcumin was dissolved...
In vitro assay
Mice
-
Mice macrophage cell line (RAW264.7)
Curcumin was dissolved and used to...
In vitro assay
Mouse
-
Mouse testicular cell lines (TM3 and TM4)
Curcumin was dissolved in dimethyl sulfoxide...
In vivo assay
Rat
-
Sprague-Dawley rat
Curcumin was prepared by dissolving it...
In vitro assay
Human
-
Human bone marrow mononuclear cells (BMMNCs)
BMMNCs were isolated from bone marrow...

Images & Validation

Key Properties

CAS Number458-37-7
MW368.38
Purity98.98%
FormulaC21H20O6
SMILESCOC1=CC(\C=C\C(=O)CC(=O)\C=C\C2=CC(OC)=C(O)C=C2)=CC=C1O
TargetHDAC,Ferroptosis,Mitophagy,Autophagy,Nrf2,Epigenetic Reader Domain,Histone Acetyltransferase,Influenza Virus
SolubilityDMSO: 265.00 mg/mL (719.37 mM), Sonication is recommended. Ethanol: 1.80 mg/mL (4.89 mM), Sonication is recommended.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

Diferuloylmethane, Curcumin, Autophagy, p300 histone acetylatransferase, Mitophagy, Mitochondrial Autophagy, Natural Yellow 3, Natural Yellow3, Natural Yellow-3, inhibit, Influenza Virus, InfluenzaVirus, Indian Saffron, Keap1-Nrf2, KEAP1-Nrf2, HAT, HATs, HistoneAcetyltransferase, Histone Acetyltransferase, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain, Ferroptosis, Turmeric yellow

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Curcumin (orb1308370)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
$ 70.00
50 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
100 mg
$ 90.00
500 mg
$ 130.00
1 g
$ 170.00
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