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Description
Research Area
Images & Validation
−| Tested Applications | ICC, IF, IHC-P, WB |
|---|---|
| Dilution Range | WB: 1:100-800, IHC-P: 1:100-600, IF/ICC: 1:100-600 |
Key Properties
−| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from human CXCR1. Please contact us for the exact immunogen sequence. The peptide is available as orb12890. |
| Target | CXCR1 |
| Molecular Weight | 40 kDa |
| Purity | Polyclonal antibodies are purified by peptide affinity chromatography |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | 10 mM PBS, 0.02% sodium azide |
| Concentration | - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.
UniProt Details
−NCBI Gene Details
−NCBI Reference Sequences
−| RefSeq | 000625 |
|---|
Protocol Information
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Dutta, Puja et al. Regulation of Staphylococcus aureus-induced CXCR1 expression via inhibition of receptor mobilization and receptor shedding during dual receptor (TNFR1 and IL-1R) neutralization Immunol Res, 67, 241-260 (2019)
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Dutta, Puja et al. Neutralization of TNF-α and IL-1β Regulates CXCL8 Production through CXCL8/CXCR1 Axis in Macrophages during Staphylococcus aureus Infection Immunol. Invest., (2020)
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Nandi, Ajeya et al. Murine macrophage response from peritoneal cavity requires signals mediated by chemokine receptor CCR-2 during Staphylococcus aureus infection Immunol Res, 64, 213-232 (2016)
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Sung Hee Jo, Ji-Ae Choi, Yun-Ji Lim, Junghwan Lee, Soo-Na Cho, Sung-Man Oh, Dam Go, Seon-Hwa Kim, Chang-Hwa Song Calreticulin modulates the intracellular survival of mycobacteria by regulating ER-stress-mediated apoptosis Oncotarget, 5, 0 (2017)
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Ajeya Nandi, Biswadev Bishayi A novel CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1 Immunology Letters, 190, (2017)
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Ajeya Nandi, Biswadev Bishayi CCR-2 neutralization augments murine fresh BMC activation by Staphylococcus aureus via two distinct mechanisms: at the level of ROS production and cytokine response Innate Immunity, 23, 345 (2017)
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Biswadev Bishayi, Ajeya Nandi, Rajen Dey, Rana Adhikary Expression of CXCR1 (IL-8 receptor A) in splenic, peritoneal macrophages and resident bone marrow cells after acute live or heat killed Staphylococcus aureus stimulation in mice Microbial Pathogenesis, 109, 131 (2017)
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Biswadev Bishayi, Rana Adhikary, Sahin Sultana, Rajen Dey, Ajeya Nandi Altered expression of CXCR1 (IL-8R) in macrophages utilizing cell surface TNFR1 and IL-1 receptor during Staphylococcus aureus infection Microbial Pathogenesis, 113, 272 (2017)
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