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CXCR2 antagonist 3

SKU: orb1688681

Description

CXCR2 antagonist 3 is a potent small molecule inhibitor of CXCR2 with double-digit nanomolar activity. It effectively reduces neutrophil and MDSC migration while promoting CD3+ T cell infiltration in tumor models, making it a valuable research tool for studying inflammation, cancer immunology, and leukocyte biology in both in vitro and in vivo settings.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2647464-92-2
MW362.38
FormulaC17H15FN2O4S
SMILESOC1=C2C(=CC=C1NC(NC3=C(C)C(F)=CC=C3)=O)C=CCS2(=O)=O
TargetCXCR,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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CXCR2 antagonist 3 (orb1688681)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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