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CYM 5442 hydrochloride

SKU: orb3033108

Description

CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS).

Images & Validation

Key Properties

CAS Number1783987-80-3
MW445.939125061035
Purity>98%
FormulaC23H28CLN3O4
SMILESCl.O1C(C2C=CC(=C(C=2)OCC)OCC)=NC(C2=CC=CC3=C2CCC3NCCO)=N1

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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100 mg
$ 1,110.00
250 mg
$ 1,740.00
1 g
$ 3,720.00
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