Cynomolgus Latent TGF-beta 1 Protein, His Tag

SKU: orb668909

Description

Cynomolgus Latent TGF-Beta 1 (C33S), His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Ser 390 (C33S) (Accession # XP_005589396.1).

Research Area

Immunology & Inflammation

Images & Validation

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Application Notes

This protein carries a polyhistidine tag at the N-terminus. The precursor proprotein is partially cleaved by FURIN to form mature Transforming growth factor beta-1 (TGF-beta-1) and Latency-associated peptide (LAP) chains with calculated MW of 12.7 kDa and 30.4 kDa respectively. The protein migrates as 50-60 kDa (precursor proprotein), 38-45 kDa (LAP) and 13 kDa (TGFB1) under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	Latent TGF-beta 1
Reactivity	Monkey
Tag	N-10×His
Molecular Weight	43.1 kDa
Expression Region	Leu 30 - Ser 390 (C33S)
Purity	90%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Latent TGF-beta 1

UniProt

XP_005589396.1

RefSeq:XP_005589396.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	XP_005589396.1

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