D-Galactose

SKU: orb1310463

Description

D-Galactose, a C-4 epimer of glucose, is a natural hexose used to form lactose. It is widely employed in research to induce aging models in animals and is utilized in various in vitro studies of carbohydrate metabolism and glycosylation.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	59-23-4
MW	180.16
Purity	99.78%
Formula	C₆H₁₂O₆
SMILES	[C@@H]([C@@H]([C@H](C=O)O)O)([C@@H](CO)O)O
Target	Endogenous Metabolite
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (18.32 mM);H2O:66 mg/mL (366.34 mM);DMSO:86.6 mg/mL (480.68 mM)

Bioactivity

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In Vivo

Chronic D-galactose exposure induces neurodegeneration by enhancing caspase-mediated apoptosis and inhibiting neurogenesis and neuron migration in mice, as well as increasing oxidative damage. Moreover, D-galactose-induced toxicity in mice is a useful model for studying the mechanisms of neurodegeneration and neuroprotective drugs and agents. D-galactose given by oral route leads to cognitive impairments in rats which are accompanied by oxidative damage. Cognitive impairments is observed in the open-field test in the 4th and 6th weeks after d-gal administration, as well as an impairment in spatial memory in the radial maze test after the 6th week of d-gal administration.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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D-(+)-Galactose, D Galactose, Endogenous Metabolite, D-Galactopyranose, DGalactose, D-Galactose, Alpha-D-galactose, a-D-galactose, EndogenousMetabolite, α-D-galactose

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Compound Identifiers

PubChem CID

3037556 ↗

Key Properties

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No computed properties available.

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D-Galactose (orb1310463)

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Applications:	IF, IHC, WB
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Purity:	Greater than 90% as determined by SDS-PAGE.
MW:	35.4 kDa
Source:	Yeast

Purity:	Greater than 90% as determined by SDS-PAGE.
MW:	35.9 kDa
Source:	Yeast

Reactivity:	All
Dynamic Range:	0.01 mmol/L - 1 mmol/L

Applications:	ELISA, IHC, WB
Reactivity:	Bovine, Human, Mouse, Porcine
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

D-Galactose

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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Key Properties

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D-Galactose (orb1310463)

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