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D-Luciferin

SKU: orb1304335

Description

D-Luciferin is the natural substrate for firefly luciferase, enabling bioluminescence through the emission of yellow-green light (~560 nm). It is widely employed in both in vitro luciferase assays and in vivo bioluminescence imaging for applications in molecular biology, oncology, and drug discovery research.

Images & Validation

Key Properties

CAS Number2591-17-5
MW280.32
Purity99.83%
FormulaC11H8N2O3S2
SMILESOC(=O)[C@H]1CS\C(N1)=c1\nc2C=CC(=O)C=c2s1
TargetOthers
Solubility10% DMSO+90% Saline:5.5 mg/mL (19.62 mM);Ethanol:1 mg/mL (3.57 mM);DMSO:55 mg/mL (196.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5.5 mg/mL (19.62 mM)

Bioactivity

In Vivo
In an immunocompetent mouse model of ovarian cancer, use of D-luciferin substrate and firefly luciferase preserves tumor-host immune interactions, since bioluminescent imaging is a more sensitive indication of tumor growth than weight gain.
In Vitro
D-luciferin reacts with luciferase, ATP and oxygen with light emission, and the light is detected by a sensitive photographic film, thereby permitting the visualization of the alkaline phosphatase-conjugated antibodies.

Storage & Handling

Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DLuciferin, D-Luciferin, D Luciferin, D-(-)-Luciferin, Beetle Luciferin, inhibit, Inhibitor, Firefly luciferin

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Key Properties

No computed properties available.

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D-Luciferin (orb1304335)

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% DMSO +
%+
% Tween 80 +
%

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10 mg
$ 90.00
50 mg
$ 130.00
100 mg
$ 160.00
200 mg
$ 220.00
500 mg
$ 340.00
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